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Succinylcholine versus rocuronium for rapid sequence intubation in intensive care

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Succinylcholine and rocuronium are widely used to facilitate rapid sequence
induction (RSI) intubation in intensive care. Concerns relate to side effects of
succinylcholine and to a slower onset and inferior intubation conditions associated
with rocuronium. So far succinylcholine and rocuronium have not been compared in
an adequately powered randomized trial in intensive care. Accordingly, the aim of the
present study was to compare the incidence of hypoxemia after rocuronium or
succinylcholine in critically ill patients requiring an emergent RSI.
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Systemic Lidocaine Decreased the Perioperative Opioid Analgesic Requirements but Failed to Reduce Discharge Time After Ambulatory Surgery

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Perioperative systemic lidocaine significantly reduces opioid requirements in the ambulatory setting without affecting time to discharge. Postoperative pain is the most common reason for delay in discharge and unplanned hospital admission after ambulatory surgery. 1–3 Because postoperative pain is to a large extent an inflammatory phenomenon, administration of systemic local anesthetics, which have inflammatory modulatory properties, 4 could significantly reduce pain and therefore allow more rapid discharge. 5 Lidocaine has an excellent safety record when administered by low-dose infusion. 5–7 However, whereas decreased hospital stay after inpatient surgery has been demonstrated, the effect of intraoperative and early postoperative lidocaine infusion on duration of stay after ambulatory surgery is not known. Although it see...
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