VASOACTIVE DRUGS IN CIRCULATORY SHOCK

Shock is the syndrome that results from failure of the cardiovascular system to
maintain adequate tissue perfusion.1 The initial priority is to maintain reasonable
hemodynamics while the etiology of shock is identified and its pathogenesis is addressed.
Hemodynamic therapy can be conceptualized in three broad categories: fluid
resuscitation, vasopressor therapy, and inotropic therapy. Fluid resuscitation is usually
the first step, but has been well described elsewhere,2 and will be considered only
peripherally; this review will focus on use of vasoactive agents for patients with shock.
When fluid administration fails to restore adequate arterial pressure and organ perfusion
in patients with shock, therapy with vasoactive agents should be initiated
.http://ajrccm.atsjournals.org/cgi/reprint/201006-0972CIv1

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