New guidelines on the diagnosis, classification, and treatment of true hypotonic hyponatremia have been published online in the European Journal of Endocrinology. The guidelines focus on managing patients, rather than on treating absolute sodium levels, the authors emphasize.
"Hyponatremia, defined as a serum sodium concentration of less than 135 mmol/L, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice," write Goce Spasovski, MD, PhD, from the State University Hospital Skopje, Macedonia, and colleagues from the Hyponatremia Guideline Development Group.
"It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life-threatening, and is associated with increased mortality, morbidity, and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic," they stress.
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