Intravenous Lidocaine:
Optimal Time of Injection before Tracheal Intubation
Stanley Tam, MD, FRCP, Frances Chung, MD, FRCP, and Michael Campbell, MD, FRCP
The circulatory stimulation accompanying laryngoscopy and tracheal intubation and its attendant poten-
tial hazards are well recognized. Many methods to attenuate this stress response have been studied,
among which intravenous (IV) lidocaine has been popular, probably because of its theoretical advan-
tages of suppressing cough reflex (1,2), preventing increases in intracranial pressure (3), attenuating cir-
culatory responses (4), and its antiarrhythmic properties (5). Abou-Madi et al. (6), in comparing two doses of intravenous lidocaine (0.75 and 1.5 mg/kg), found that the higher dose was more effective in attenuating circulatory responses to tracheal intubation. The time of injection of IV lidocaine for this purpose has, however, been either not clearly specified (6) or chosen on an empirical basis (7). There has been no evaluation of the optimal time of injection of IV lidocaine for the attenuation of circulatory responses secondaryto tracheal intubation.
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