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Randomized controlled trial comparing morphine or clonidine with bupivacaine for caudal analgesia in children undergoing upper abdominal surgery

Par

  • P. Singh3

    • +Author Affiliations
    1. 1Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital, New Delhi, India
    2. 2Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India
    3. 3BL Kapoor Memorial Hospital, New Delhi, India
    1. *Corresponding author. 595 GF, Sector 14, Gurgaon 122007, India. E-mail:kumarnishant@yahoo.co.uk
    • Accepted September 1, 2010.
     
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    Abstract

    Background Various additives have been used to increase the duration of analgesia provided by bupivacaine administered by single-shot caudal injection in children.

    Key points

    • The use of clonidine or morphine to prolong analgesia provided by caudal bupivacaine was compared in children undergoing upper abdominal surgery.
    • Clonidine increased the duration of analgesia and sedation with fewer side-effects compared with morphine.
    • Clonidine was a safe and effective supplement to caudal bupivacaine analgesia for upper abdominal surgery.

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