Randomized controlled trial comparing morphine or clonidine with bupivacaine for caudal analgesia in children undergoing upper abdominal surgery

R. Singh1, 

N. Kumar2,* and 

P. Singh3

+Author Affiliations

1. ¹Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital, New Delhi, India
2. ²Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India
3. ³BL Kapoor Memorial Hospital, New Delhi, India

1. *Corresponding author. 595 GF, Sector 14, Gurgaon 122007, India. E-mail:kumarnishant@yahoo.co.uk

• Accepted September 1, 2010.

 

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Abstract

Background Various additives have been used to increase the duration of analgesia provided by bupivacaine administered by single-shot caudal injection in children.

Key points

• The use of clonidine or morphine to prolong analgesia provided by caudal bupivacaine was compared in children undergoing upper abdominal surgery.
• Clonidine increased the duration of analgesia and sedation with fewer side-effects compared with morphine.
• Clonidine was a safe and effective supplement to caudal bupivacaine analgesia for upper abdominal surgery.
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